Etomidate bulk supplier for pharma manufacturers

Etomidate 2 mg/mL Suppliers & Bulk Manufacturers

Available Forms: Intravenous (IV) Injection/Emulsion

Available Strengths: 2 mg/mL

Reference Brands: Amidate(US)

Etomidate 2 mg/mL injection, available as a propylene glycol solution or a lipid emulsion, is an intravenous induction agent for anaesthesia and rapid sequence intubation. For hospital pharmacies, critical care units, importers and tender buyers.

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Product Description:

Etomidate is a short-acting intravenous hypnotic from the imidazole group. It enhances GABA activity at GABA-A receptors and brings on sleep within about a minute of a bolus dose. This page covers 2 mg/mL presentations, made either as a clear solution in propylene glycol or as a lipid emulsion in soya oil and medium-chain triglycerides. The emulsion was developed to cause less pain on injection and less venous irritation. Etomidate has no analgesic effect, so pain relief is given alongside it.

Anaesthetists and emergency physicians use it to induce anaesthesia and for rapid sequence intubation, because it causes little fall in blood pressure. That makes it a common choice for shocked or frail patients. A typical adult dose is about 0.3 mg/kg by slow intravenous injection. Even one dose briefly suppresses adrenal cortisol production, so it is not used as an infusion for sedation, and clinicians weigh this effect in sepsis. Myoclonus and nausea on recovery are common. Only staff trained in airway management should give it.

Sourcing notes. Etomidate is a prescription-only hospital medicine. State whether your formulary needs the solution or the emulsion, plus vial or ampoule size (10 mL holding 20 mg is usual) and pack count. The emulsion must not be frozen or used if it has separated. Request the dossier in CTD or ACTD format, with Zone IVb stability data for hot, humid markets. Ask for a certificate of analysis for each batch, with sterility and endotoxin results, the GMP certificate for the finished-product site and a CoPP.

Etomidate — third party manufacturing & bulk supply

Etomidate 2 mg/mL is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.

Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.

Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Etomidate is supplied as Intravenous (IV) Injection/Emulsion — supplied in more than one dosage form, each with its own manufacturing economics, so the indicative MOQ is a minimum order value of USD 5,000 per product. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Etomidate listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

Etomidate injection is used for the induction of general anesthesia and for short surgical or diagnostic procedures. It is commonly administered intravenously to induce rapid unconsciousness, especially in emergency settings where cardiovascular stability is important.

Etomidate injection is made from etomidate, a short-acting intravenous anesthetic agent. It works by enhancing the activity of gamma-aminobutyric acid (GABA) in the central nervous system, producing hypnosis with minimal effects on heart rate and blood pressure.

The most well-known trade name is Amidate.

Amidate was originally developed and marketed by Janssen Pharmaceuticals. Currently, etomidate injection is manufactured and distributed by various pharmaceutical companies worldwide depending on regional approvals.

The generic name is etomidate.

The brand name is Amidate.

Etomidate injection is manufactured in GMP-certified pharmaceutical facilities in the United States, Europe, India, and other regulated markets depending on the marketing authorization holder and supplier. Specific manufacturing locations vary by brand and batch.