Eptifibatide 2 mg/mL Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 2 mg/mL

Reference Brands: Integrilin (USA)

Category: Heart Disorder

Eptifibatide is a Heart Disorder product available as Injection in strengths 2 mg/mL. It corresponds to the reference brand Integrilin (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Eptifibatide is a potent intravenous antiplatelet agent belonging to the glycoprotein IIb/IIIa inhibitor class, widely used to reduce ischemic cardiac events in high-risk cardiovascular patients. It is FDA-approved for the medical management of unstable angina and non-ST elevation myocardial infarction (NSTEMI), as well as for patients undergoing percutaneous coronary intervention (PCI), including intracoronary stent placement. Clinical evidence from the IMPACT-II trial demonstrated that eptifibatide, when used in combination with heparin and aspirin, significantly reduces ischemic complications following PCI, particularly in patients with unstable angina.

Eptifibatide is marketed under the brand name Integrilin and was developed by Millennium Pharmaceuticals, with co-promotion by Schering-Plough/Essex. Structurally, it is a synthetic cyclic heptapeptide derived from a disintegrin protein originally identified in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri). Pharmacologically, it acts as a reversible arginine-glycine-aspartate (RGD) mimetic that inhibits platelet aggregation by blocking fibrinogen binding to activated glycoprotein IIb/IIIa receptors on platelets. Eptifibatide has a rapid onset of action and a short half-life, making it suitable for controlled use in acute cardiac care settings.