Ensifentrine 3 mg per 2.5 mL Suppliers & Bulk Manufacturers
Available Forms: Inhalation solution
Available Strengths: 3 mg per 2.5 mL
Reference Brands: Ohtuvayre (USA)
Category: Respiratory Disorder
Ensifentrine is a Respiratory Disorder product available as Inhalation solution in strengths 3 mg per 2.5 mL. It corresponds to the reference brand Ohtuvayre (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.
Product Description:
Ensifentrine is an inhaled medication used for the maintenance treatment of chronic obstructive pulmonary disease (COPD) in adults. It is marketed under the brand name Ohtuvayre and represents a novel therapeutic approach by combining dual inhibition of phosphodiesterase 3 (PDE3) and phosphodiesterase 4 (PDE4) in a single molecule. This dual mechanism allows ensifentrine to deliver both bronchodilator and anti-inflammatory effects, addressing key pathological features of COPD.
As a PDE3 inhibitor, ensifentrine helps relax airway smooth muscle, leading to bronchodilation and improved airflow. At the same time, its PDE4 inhibitory activity reduces airway inflammation, which contributes to symptom control and disease management. Ensifentrine is administered by inhalation, allowing targeted delivery directly to the lungs and minimizing systemic exposure.
Ensifentrine is indicated for long-term COPD management and is used to improve lung function and reduce respiratory symptoms. Its inhaled formulation makes it suitable for patients who require consistent, localized therapy. By combining bronchodilation and anti-inflammatory action in one treatment, ensifentrine offers a differentiated and effective option for personalized respiratory care in adult COPD patients.
Ensifentrine — third party manufacturing & bulk supply
Ensifentrine 3 mg per 2.5 mL is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
Indicative minimum order quantity
Ensifentrine is supplied as Inhalation solution — a dosage form priced by order value, so the indicative MOQ is a minimum order value of USD 5,000 per product. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.
Manufacturers of Ensifentrine listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.
Request a quote for Ensifentrine →Frequently Asked Questions
Ensifentrine is used for the maintenance treatment of chronic obstructive pulmonary disease (COPD) in adults. It helps improve lung function and reduce respiratory symptoms associated with COPD.
Ensifentrine is a small-molecule, dual phosphodiesterase (PDE) inhibitor that selectively inhibits PDE3 and PDE4 enzymes involved in airway inflammation and bronchoconstriction.
The trade name of ensifentrine is Ohtuvayre.
Ensifentrine is developed and marketed by Verona Pharma.
The generic name is ensifentrine.
The brand name is Ohtuvayre.
Ensifentrine is manufactured in GMP-compliant pharmaceutical facilities for commercial supply in the United States.
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