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Ensifentrine bulk supplier for pharma manufacturers

Ensifentrine 3 mg per 2.5 mL Suppliers & Bulk Manufacturers

Available Forms: Inhalation solution

Available Strengths: 3 mg per 2.5 mL

Reference Brands: Ohtuvayre (USA)

Category: Respiratory Disorder

Ensifentrine is a Respiratory Disorder product available as Inhalation solution in strengths 3 mg per 2.5 mL. It corresponds to the reference brand Ohtuvayre (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

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Product Description:

Ensifentrine is an inhaled medication used for the maintenance treatment of chronic obstructive pulmonary disease (COPD) in adults. It is marketed under the brand name Ohtuvayre and represents a novel therapeutic approach by combining dual inhibition of phosphodiesterase 3 (PDE3) and phosphodiesterase 4 (PDE4) in a single molecule. This dual mechanism allows ensifentrine to deliver both bronchodilator and anti-inflammatory effects, addressing key pathological features of COPD.

As a PDE3 inhibitor, ensifentrine helps relax airway smooth muscle, leading to bronchodilation and improved airflow. At the same time, its PDE4 inhibitory activity reduces airway inflammation, which contributes to symptom control and disease management. Ensifentrine is administered by inhalation, allowing targeted delivery directly to the lungs and minimizing systemic exposure.

Ensifentrine is indicated for long-term COPD management and is used to improve lung function and reduce respiratory symptoms. Its inhaled formulation makes it suitable for patients who require consistent, localized therapy. By combining bronchodilation and anti-inflammatory action in one treatment, ensifentrine offers a differentiated and effective option for personalized respiratory care in adult COPD patients.

Ensifentrine — third party manufacturing & bulk supply

Ensifentrine 3 mg per 2.5 mL is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Ensifentrine is supplied as Inhalation solution — a dosage form priced by order value, so the indicative MOQ is a minimum order value of USD 5,000 per product. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Ensifentrine listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions


Ensifentrine is used for the maintenance treatment of chronic obstructive pulmonary disease (COPD) in adults. It helps improve lung function and reduce respiratory symptoms associated with COPD.


Ensifentrine is a small-molecule, dual phosphodiesterase (PDE) inhibitor that selectively inhibits PDE3 and PDE4 enzymes involved in airway inflammation and bronchoconstriction.


The trade name of ensifentrine is Ohtuvayre.


Ensifentrine is developed and marketed by Verona Pharma.


The generic name is ensifentrine.


The brand name is Ohtuvayre.


Ensifentrine is manufactured in GMP-compliant pharmaceutical facilities for commercial supply in the United States.

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