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DIMETHYL FUMARATE  Tablet bulk supplier for pharma manufacturers

Dimethyl Fumarate Tablet Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 30 mg ,120 mg

Reference Brands: Skilarence (EU)

Category: Multiple sclerosis

Capsule is a medicine that contains the active substance dimethyl fumarate. It is used to treat relapsing-remitting multiple sclerosis (MS) in adult patients. MS is a chronic disorder that can affect your spinal cord, brain, and optic nerves in the eyes. Relapsing-remitting MS is characterized by repeated attacks of symptoms.

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Product Description:

Symptoms vary from person to person but typically include walking difficulties, feeling off-balance and visual difficulties (e.g., blurred or double vision). Before taking this medication, you need to inform your physician if you have kidney disorders, liver disorders, gastrointestinal problems, brain or other infections. This medication is not recommended for adolescents and children.

Dimethyl fumarate (DMF) is a methyl ester of fumaric acid with potent immunomodulatory properties, making it a versatile therapy for both neurological and dermatological conditions. It is designed to modulate immune system activity without causing significant immunosuppression, offering therapeutic benefits while maintaining safety.

In neurology, dimethyl fumarate is approved in the United States under the brand name Tecfidera for the treatment of adults with relapsing forms of multiple sclerosis (MS). It helps reduce relapse frequency and slows the progression of disability in patients with relapsing-remitting MS.

In dermatology, dimethyl fumarate is used in the management of moderate-to-severe plaque psoriasis. In the European Union, it is marketed as Skilarence, while in Germany, DMF combined with other fumaric acid esters is licensed as Fumaderm. These therapies modulate inflammatory responses in the skin and provide an effective treatment option for patients with psoriasis.

Dimethyl fumarate is available as oral formulations in various strengths, depending on the market and indication. Its unique mechanism of action, combined with an established safety profile, makes it a valuable option for patients requiring long-term management of autoimmune or inflammatory conditions.

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Frequently Asked Questions

Dimethyl Fumarate is used primarily for the treatment of multiple sclerosis (MS), specifically relapsing forms of MS. It helps reduce the frequency of relapses and slows the progression of physical disability. It is also used in some cases to manage psoriasis due to its immunomodulatory and anti-inflammatory effects.

Dimethyl Fumarate is a synthetic derivative of fumaric acid. It works by activating the Nrf2 pathway, which provides antioxidant effects and modulates immune system activity.

Dimethyl Fumarate is marketed under several trade names, including Tecfidera, Skilarence, and other regional brand names depending on the market.

The innovator brand Tecfidera was developed by Biogen. Generic versions and other approved brands are manufactured by various pharmaceutical companies globally.

The complete generic name is dimethyl fumarate.

Brand names include Tecfidera, Skilarence, and other country-specific brands depending on regulatory approvals and manufacturers.

Dimethyl Fumarate is manufactured in multiple countries including the USA, EU member states, and India, depending on the brand and manufacturer.

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