Cyclosporine Injection 50 mg/mL Suppliers & Bulk Manufacturers
Available Forms: Injection
Available Strengths: 50 mg/mL
Reference Brands: Sandimmune (USA)
Category: Transplant
This injection contains Cyclosporin which is an immunosuppressive agents. Immunosuppressive agents are the drugs that suppress or reduces the strength of our immune system.
Product Description:
This injection is used in preventing organ rejection in patients who have had an organ transplant, bone marrow and stem cell transplantation.
Cyclosporine is a potent immunosuppressive agent widely used to prevent organ rejection following allogeneic transplantation, particularly in kidney, liver, and heart transplant patients. It works by selectively inhibiting T-lymphocyte activation, thereby suppressing immune responses that can lead to graft rejection. Due to its targeted immunomodulatory action, cyclosporine plays a critical role in transplant medicine.
Cyclosporine exerts its effect by inhibiting calcineurin, which blocks the transcription of interleukin-2 and other cytokines essential for T-cell activation. Due to its narrow therapeutic index, treatment requires careful dosing, therapeutic drug monitoring, and regular assessment of renal function and other safety parameters. Cyclosporine remains a cornerstone therapy in immunosuppressive treatment protocols worldwide.
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Frequently Asked Questions
Cyclosporine is used as an immunosuppressive medicine to prevent organ rejection after kidney, liver, and heart transplants. It is also used in autoimmune and inflammatory conditions such as rheumatoid arthritis, psoriasis, nephrotic syndrome, uveitis, and certain severe skin and eye disorders where suppression of the immune response is required.
Cyclosporine is a cyclic polypeptide immunosuppressant originally derived from the fungus Tolypocladium inflatum. The medicinal product is synthetically manufactured for pharmaceutical use.
Cyclosporine is marketed under several trade names globally, including Sandimmune, Neoral, Gengraf, and Restasis (ophthalmic formulation).
Cyclosporine is manufactured by multiple pharmaceutical companies worldwide. The original innovator brands were developed by Novartis, while many generic versions are produced by various global pharmaceutical manufacturers.
The complete generic name is cyclosporine (also known as ciclosporin).
Brand names of cyclosporine include Sandimmune, Neoral, Gengraf, Restasis, and other regional brands depending on country and formulation.
Cyclosporine is manufactured in multiple countries including the USA, EU nations, India, and other pharmaceutical manufacturing hubs, depending on the brand and manufacturer.
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