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Crizanlizumab bulk supplier for pharma manufacturers

Crizanlizumab 100 mg/10 mL (10 mg/mL) Suppliers & Bulk Manufacturers

Available Forms: IV Infusion

Available Strengths: 100 mg/10 mL (10 mg/mL)

Reference Brands: Adakveo®(EU & US)

Category: Anemia

Crizanlizumab (Adakveo®) is an FDA- and EMA-approved IV biologic for sickle cell disease, available for B2B pharma distribution in the US and EU to reduce pain crises in affected patients.

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📘 Sourcing Guide

Product Description:

rizanlizumab (Adakveo®) is a breakthrough biologic therapy for sickle cell disease, available for B2B pharmaceutical distribution across the US and EU markets. It is a humanized monoclonal antibody (anti-P-selectin) used to reduce the frequency of painful vaso-occlusive crises in patients with sickle cell anemia. Approved by the FDA and EMA, Crizanlizumab is supplied as a 100 mg/10 mL IV infusion, ideal for hospital and specialty clinic use. Pharma B2B partners benefit from secure supply chains, regulatory-compliant sourcing, and access to one of the most innovative therapies in hematology. Reliable distribution and market-ready packaging ensure smooth commercialization across regulated markets.

Crizanlizumab — third party manufacturing & bulk supply

Crizanlizumab 100 mg/10 mL (10 mg/mL) is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

What to include when you enquire

  • Destination market — determines which manufacturers hold the right site-level approvals
  • First order quantity and estimated annual volume
  • Whether you need a registration dossier or the product is already registered
  • Packaging, labelling and language requirements
  • Incoterms and required shelf life

Manufacturers of Crizanlizumab listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.

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Frequently Asked Questions

Crizanlizumab is used to reduce the frequency of vaso-occlusive crises in patients with sickle cell disease. It helps prevent painful crises by decreasing the adhesion of sickled red blood cells and other blood components to blood vessel walls.

It is made from a humanized monoclonal antibody (IgG2) that targets P-selectin, a cell-adhesion protein involved in vaso-occlusion.

The trade name is Adakveo.

It is manufactured by Novartis.

The generic name is Crizanlizumab-tmca.

The brand name is Adakveo.

It is manufactured in various Novartis production facilities, including sites in Europe and the United States.

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