Apomorphine Hydrochloride Injection 10 mg/mL, 20 mg/mL Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 10 mg/mL, 20 mg/mL

Reference Brands: Apokyn (USA)

Category: Neurology

Apomorphine Hydrochloride Injection is a Neurology product available as Injection in strengths 10 mg/mL, 20 mg/mL. It corresponds to the reference brand Apokyn (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Apomorphine Hydrochloride, marketed under the brand name Apokyn, is a synthetic aporphine derivative that functions primarily as a non-selective dopamine agonist. It activates D2-like dopamine receptors and, to a lesser extent, D1-like receptors, making it effective in the management of motor symptoms associated with advanced Parkinson’s disease. Additionally, apomorphine exhibits antagonistic activity at 5-HT2 and α-adrenergic receptors, contributing to its overall pharmacological profile.

Although historically derived from morphine through chemical modification, apomorphine does not contain morphine, does not share its opioid structure, and does not bind to opioid receptors. Its name reflects its origin as a morphine decomposition product rather than any opioid activity. Apomorphine is used clinically to provide rapid relief of “off” episodes in Parkinson’s disease patients, restoring mobility and reducing symptoms such as bradykinesia, rigidity, and tremor. Administered subcutaneously or as a sublingual film, it acts quickly to improve motor function and is typically used under strict medical supervision due to potential side effects like nausea, hypotension, and sedation.