Amantadine

Form: Tablet; Capsule; Oral Solution and ER Capsule

Strength: Tab -100 mg; Capsule- 100 mg; Oral solution - 50 mg/5 mL; Extended-release capsule (ER) - 129 mg, 193 mg

Reference Brands: Symmetrel(EU & US); Osmolex ER(US), Gocovri(US)

Category: Anti Viral

Amantadine is an antiviral and CNS-active medication used for the treatment of Parkinson’s disease, drug-induced extrapyramidal symptoms, and formerly for Influenza A. It acts as an NMDA receptor antagonist and M2 ion channel blocker, helping reduce symptoms of tremor and dyskinesia. Available in 100 mg tablets, capsules, oral solution, and extended-release forms, Amantadine is FDA and EMA approved. Though antiviral use has declined due to resistance, it remains valuable in neurology. Brand names include Symmetrel, Gocovri, and Osmolex ER. Amantadine is widely used in elderly care and neurorehabilitation for its dopaminergic activity and fatigue-reducing effects.