Alvimopan 12 mg Suppliers & Bulk Manufacturers

Available Forms: Capsules

Available Strengths: 12 mg

Reference Brands: Entereg (USA)

Category: Gastrointestinal Drugs

Alvimopan 12 mg capsules are a peripherally acting opioid blocker that speeds recovery of bowel function after bowel resection surgery, given short-term in hospital. It does not reduce the pain relief from opioids. The reference brand is Entereg, and it is available only in a few markets. Ask PharmaTradz for a quote; we confirm the manufacturer, registration documents and lead time for your country.

Product Description:

Alvimopan, marketed under the trade name Entereg, is a peripherally acting μ-opioid receptor antagonist used to treat postoperative ileus. Unlike centrally acting opioid antagonists, alvimopan has limited ability to cross the blood–brain barrier, allowing it to block μ-opioid receptors in the gastrointestinal tract without reversing the analgesic effects of opioids in the central nervous system. This selective action helps patients recover bowel function more quickly after surgery while still managing pain effectively with opioid medications.

Alvimopan is primarily prescribed for hospitalized patients following bowel resection surgery. It is administered orally in a controlled hospital setting, typically starting prior to surgery and continuing for a limited number of doses postoperatively. By stimulating gastrointestinal motility and reducing the duration of postoperative ileus, alvimopan can shorten hospital stays and improve patient comfort and recovery outcomes. Its use is restricted to FDA-approved indications due to potential cardiovascular risks with long-term administration. When used appropriately under medical supervision, alvimopan is an effective agent for managing postoperative gastrointestinal complications without compromising pain control.