Acoramidis Hydrochlorid 400 mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 400 mg

Reference Brands: Attruby (USA), Beyonttra (EU)

Category: Heart Disorder

Acoramidis Hydrochlorid is a Heart Disorder product available as Tablets in strengths 400 mg. It corresponds to the reference brands Attruby (USA), Beyonttra (EU). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Acoramidis, marketed under the brand name Attruby, is a disease-modifying medication used for the treatment of cardiomyopathy associated with transthyretin-mediated amyloidosis (ATTR-CM) in adults. It is a near-complete (>90%) transthyretin stabilizer, developed to mimic the protective properties of the naturally occurring T119M mutation, which helps prevent the misfolding and aggregation of transthyretin proteins. By stabilizing the transthyretin tetramer, Acoramidis reduces the formation of amyloid deposits in cardiac tissues, addressing the underlying cause of ATTR-CM rather than just managing symptoms. This mechanism helps slow the progression of the disease, improve cardiac function, and reduce the risk of cardiovascular-related hospitalizations and death in patients with wild-type or variant ATTR-CM. Administered orally in tablet form, Acoramidis provides a convenient treatment option for long-term management. Its development represents a significant advancement in targeted therapies for amyloid cardiomyopathy, offering patients a clinically proven approach to modifying disease progression. Attruby is manufactured under stringent quality standards and is approved for use in