Bupivacaine Hydrochloride Injection shortage (US): status and presentations
Shortage United States · first listed 20 February 2018 · updated 15 October 2026
| Dosage form | Injection |
|---|---|
| Therapy area | Anesthesia, Analgesia/Addiction |
| Presentations | 4 unavailable, 5 limited, 48 available |
| Source | US FDA Drug Shortage Database (openFDA), checked 19 October 2026 |
Presentations affected
- Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL — Unavailable
- Marcaine, Injection, 0.75% 15 mg/2 mL (7.5 mg/mL) in Dextrose 8.25% — Unavailable
- Sensorcaine, Injection, 2.5 mg/1 mL — Unavailable
- Sensorcaine, Injection, 5 mg/1 mL — Unavailable
- Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL — Limited Availability
- Bupivacaine Hydrochloride, Injection, 5 mg/1 mL — Limited Availability
- Bupivacaine Hydrochloride PRESERVATIVE FREE, Injection, 2.5 mg/1 mL 5mg / 1mL — Available
- Bupivacaine Hydrochloride, Injection, 125 mg/50 mL (2.5 mg/mL) — Available
- Bupivacaine Hydrochloride, Injection, 150 mg/30 mL (5 mg/mL) — Available
- Bupivacaine Hydrochloride, Injection, 225 mg/30 mL (7.5 mg/mL) — Available
- Bupivacaine Hydrochloride, Injection, 25 mg/10 mL (2.5 mg/mL) — Available
- Bupivacaine Hydrochloride, Injection, 250 mg/50 mL (5 mg/mL) — Available
- Bupivacaine Hydrochloride, Injection, 50 mg/10 mL (5 mg/mL) — Available
- Bupivacaine Hydrochloride, Injection, 75 mg/30 mL (2.5 mg/mL) — Available
- Bupivacaine Hydrochloride, Injection, Bupivacaine Spinal 15 mg/2 mL (7.5 mg/mL in 8.25% dextrose) — Available
- Marcaine, Injection, 0.75% 15 mg/2 mL — Available
- Marcaine, Injection, 150 mg/30 mL (5 mg/mL) — Available
- Marcaine, Injection, 225 mg/30 mL — Available
- Marcaine, Injection, 25 mg/10 mL (2.5 mg/mL) — Available
- Marcaine, Injection, 250 mg/50 mL — Available
- Marcaine, Injection, 50 mg/10 mL (5 mg/mL) — Available
- Marcaine, Injection, 75 mg/30 mL (2.5 mg/mL) — Available
- Marcaine, Injection, Marcaine 125 mg/50 mL (2.5 mg/mL) — Available
- Marcaine, Injection, Marcaine 225 mg/30 mL (7.5 mg/mL) — Available
- Marcaine, Injection, Marcaine 75 mg/10 mL (7.5 mg/mL) — Available
- Sensorcaine, Injection, 7.5 mg/1 mL — Available
Strengths and packs as listed by the regulator. Manufacturer names and product codes are not shown.
What buyers can do
- Check whether other registered presentations or strengths can be used, and ask your wholesaler about allocation.
- For hospital and tender supply, look for manufacturers that already hold an approval in your market and can increase output.
- In a critical shortage, the FDA can allow temporary importation of a version approved in a well-regulated market. That decision is made by the FDA, case by case.
- Qualify any new source as carefully as at any other time: GMP certificate, registration status and a certificate of analysis for each batch.
See the product page for Bupivacaine Hydrochloride Injection on PharmaTradz.
More: where licensed suppliers can step in during US shortages.
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For information only. Shortage status changes often; confirm with the regulator before making decisions. Brand names, where shown, are trademarks of their owners.
