Remimazolam Besylate 20 mg, 50 mg Suppliers & Bulk Manufacturers
Available Forms: Injection
Available Strengths: 20 mg, 50 mg
Reference Brands: Byfavo (USA/EU)
Category: Anaesthetics
Remimazolam Besylate is a Anaesthetics product available as Injection in strengths 20 mg, 50 mg. It corresponds to the reference brand Byfavo (USA/EU). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.
Product Description:
Remimazolam besylate is a short-acting benzodiazepine derivative with sedative-hypnotic properties, structurally related to midazolam. It is designed for intravenous use and is primarily indicated for procedural sedation and anesthesia in adults. Remimazolam acts by selectively targeting the gamma-aminobutyric acid (GABA)-A receptor complex on neuronal cell membranes. Upon binding to a specific allosteric site on the GABA-A chloride ionophore receptor, it enhances the affinity of GABA for the receptor.
This interaction increases the frequency of chloride channel opening, leading to an influx of chloride ions into the neuron. The resulting increase in chloride ion conductance causes neuronal hyperpolarization, inhibition of action potential firing, and a reduction in neuronal excitability, producing its sedative and hypnotic effects. Remimazolam besylate is characterized by a rapid onset and short duration of action due to its metabolism by tissue esterases, independent of hepatic cytochrome enzymes.
Its pharmacokinetic profile allows for predictable sedation, rapid recovery, and improved control during short medical procedures. Additionally, its effects can be reversed with flumazenil, providing an added safety advantage in clinical settings.
Remimazolam Besylate — third party manufacturing & bulk supply
Remimazolam Besylate 20 mg, 50 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
What to include when you enquire
- Destination market — determines which manufacturers hold the right site-level approvals
- First order quantity and estimated annual volume
- Whether you need a registration dossier or the product is already registered
- Packaging, labelling and language requirements
- Incoterms and required shelf life
Manufacturers of Remimazolam Besylate listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.
Request a quote for Remimazolam Besylate →The Trade Mark owner has been correctly identified under the heading Manufacturer / TM Owner as required by the Act.
Frequently Asked Questions
Remimazolam besylate is used for procedural sedation and anesthesia in adults. It is administered intravenously to induce and maintain sedation during short diagnostic or therapeutic procedures, and in some regions it is also approved for induction and maintenance of general anesthesia.
Remimazolam besylate is a synthetic benzodiazepine derivative formulated as the besylate salt. It is designed to be ultra-short acting and is rapidly metabolized by tissue esterases, independent of liver cytochrome enzymes.
The trade name of remimazolam besylate is Byfavo. In the United States, it is marketed as BYFAVO, while in the European Union and the United Kingdom it is marketed as Byfavo.
Remimazolam besylate was originally developed by PAION AG. In the United States, BYFAVO is commercialized by Eagle Pharmaceuticals, while in Europe and the UK it is marketed through PAION and its regional partners.
The generic name is remimazolam besylate.
The brand name of remimazolam besylate is Byfavo (BYFAVO in the USA).
Remimazolam besylate is manufactured at GMP-approved pharmaceutical manufacturing facilities, with production and supply distributed across the United States and Europe depending on the brand owner and regional regulatory approvals.
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