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Pemetrexed dipotassium bulk supplier for pharma manufacturers

Pemetrexed Dipotassium 100 mg, 500 mg Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 100 mg, 500 mg

Reference Brands: Alimta (USA), Pemfexy (USA)

Category: Oncology Cancer Care

Pemetrexed Dipotassium is a Oncology Cancer Care product available as Injection in strengths 100 mg, 500 mg. It corresponds to the reference brands Alimta (USA), Pemfexy (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

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Product Description:

Pemetrexed dipotassium, marketed under brand names such as Alimta, is a chemotherapy medication used for the treatment of malignant pleural mesothelioma and non-small cell lung cancer (NSCLC). It is particularly indicated for the treatment of unresectable pleural mesothelioma, often in combination with cisplatin, for patients who are not candidates for curative surgery. Pemetrexed interferes with folate-dependent metabolic processes, inhibiting the synthesis of DNA, RNA, and proteins in rapidly dividing cancer cells, thereby slowing tumor growth and inducing cell death. In non-small cell lung cancer, Pemetrexed is approved as a first-line therapy in combination with cisplatin for locally advanced or metastatic disease, as well as for maintenance therapy in patients showing response to initial treatment. Its targeted action against rapidly proliferating cells makes it an effective option in oncology, providing a clinically established approach for managing these aggressive cancers. Pemetrexed is administered intravenously under professional supervision and can be used alone or in combination with other chemotherapeutic agents to enhance therapeutic efficacy. Its widespread use and proven effectiveness have made it a cornerstone in the management of pleural mesothelioma and non-squamous NSCLC.

Pemetrexed Dipotassium — third party manufacturing & bulk supply

Pemetrexed Dipotassium 100 mg, 500 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Pemetrexed Dipotassium is supplied as Injection — an injectable dosage form, so the indicative MOQ is 50,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Pemetrexed Dipotassium listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions


Pemetrexed dipotassium is used in the treatment of malignant pleural mesothelioma and non‑small cell lung cancer (NSCLC), particularly in non‑squamous histology, as initial therapy in combination with platinum chemotherapy and as maintenance therapy following initial treatment.


It is the dipotassium salt form of pemetrexed, a folate analog metabolic inhibitor with a chemical structure designed to mimic folate and block enzymes needed for DNA and RNA synthesis.


Trade names include Alimta and Pemfexy, along with various generic injection products in different regions.


The original branded product Alimta is manufactured by Eli Lilly and Company. Pemfexy and other generic pemetrexed injections are produced by multiple pharmaceutical manufacturers.


Pemetrexed dipotassium


Alimta, Pemfexy, Axtle, and generic equivalents


Manufactured under regulated pharmaceutical standards by Eli Lilly and other licensed manufacturers in various countries for distribution in the USA, EU, UK, and other regions.

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