Palonosetron 0.25 Mg Injection 0.25 mg/5 mL vial Suppliers & Bulk Manufacturers
Available Forms: Injection
Available Strengths: 0.25 mg/5 mL vial
Reference Brands: Posfrea (USA)
Category: Oncology Cancer Care
Palonosetron 0.25 mg/5 ml injection is a long-acting 5-HT3 antagonist given as a single dose before chemotherapy to prevent nausea and vomiting, including delayed vomiting. It lasts much longer than ondansetron or granisetron. The original brand is Aloxi, and generic versions are widely available. PharmaTradz sources it for importers, hospitals and tenders, and shares GMP certificates and CoA before you commit.
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Product Description:
Palonosetron Injection 0.25 mg/5 mL is a 5-HT3 receptor antagonist used to prevent chemotherapy-induced nausea and vomiting (CINV). It is particularly effective for patients undergoing highly emetogenic chemotherapy regimens. Approved in both the U.S. (under the brand name Aloxi) and the EU, Palonosetron is available as a single-dose 0.25 mg/5 mL vial for IV administration. This drug is essential in oncology B2B distribution, helping oncology centers and hospitals manage the side effects of chemotherapy, ensuring better patient outcomes by reducing nausea and vomiting after treatment.
Palonosetron 0.25 Mg Injection — third party manufacturing & bulk supply
Palonosetron 0.25 Mg Injection 0.25 mg/5 mL vial is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
Indicative minimum order quantity
Palonosetron 0.25 Mg Injection is supplied as Injection — an injectable dosage form, so the indicative MOQ is 50,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.
Manufacturers of Palonosetron 0.25 Mg Injection listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.
Request a quote for Palonosetron 0.25 Mg Injection →Usually answered within 48 hours, with matched manufacturers, indicative prices and document status.
Frequently Asked Questions
Palonosetron is used to prevent nausea and vomiting associated with cancer chemotherapy and surgical procedures. It is particularly effective in preventing delayed nausea and vomiting that may occur several hours to days after treatment.
Palonosetron is a chemically synthesized compound that belongs to the class of serotonin (5-HT₃) receptor antagonists. It works by blocking serotonin receptors involved in triggering nausea and vomiting.
Palonosetron is marketed under the trade name Aloxi.
The original brand Aloxi was developed and marketed by Helsinn Healthcare. Today, palonosetron is also manufactured by multiple pharmaceutical companies worldwide as branded and generic versions.
The generic name is palonosetron (commonly used as palonosetron hydrochloride).
The most well-known brand name is Posfrea, Aloxi, along with various country-specific branded generics.
Palonosetron is manufactured in several countries including the USA, EU nations, India, and other regulated markets by approved pharmaceutical manufacturers following international quality and regulatory standards.
Its half-life is about 40 hours, so a single 0.25 mg intravenous dose before chemotherapy protects against both acute and delayed nausea.
Yes. It is often given with dexamethasone and an NK1 blocker such as netupitant (Akynzeo is the fixed combination).
As 0.25 mg/5 ml solution in vials or pre-filled syringes, stored at room temperature.
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