Nintedanib 100 mg, 150 mg Suppliers & Bulk Manufacturers

Available Forms: Capsules

Available Strengths: 100 mg, 150 mg

Reference Brands: Ofev (USA, EU), Vargatef (EU)

Category: Oncology Cancer Care

Nintedanib is a Oncology Cancer Care product available as Capsules in strengths 100 mg, 150 mg. It corresponds to the reference brands Ofev (USA, EU), Vargatef (EU). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Nintedanib is an oral medication prescribed for the treatment of idiopathic pulmonary fibrosis (IPF) and certain types of non-small-cell lung cancer (NSCLC) when used in combination with other therapies. It belongs to the class of small-molecule tyrosine kinase inhibitors and works by targeting multiple growth factor receptors, including VEGFR, FGFR, and PDGFR. By inhibiting these pathways, nintedanib reduces fibroblast proliferation, slows ongoing fibrotic processes, and delays progression of irreversible tissue damage.

Sold under the brand names Ofev and Vargatef, nintedanib is available in oral capsule formulations, typically 100 mg and 150 mg. It is also indicated for systemic sclerosis-associated interstitial lung disease and progressive fibrosing interstitial lung disease, making it a critical therapy for patients with progressive fibrotic conditions.

Nintedanib therapy requires careful patient monitoring due to potential adverse effects, including liver enzyme elevations and gastrointestinal issues. Its pharmacokinetic profile allows for targeted, individualized treatment, and understanding drug interactions is essential to optimize efficacy and safety. Nintedanib provides clinicians with an effective option to manage fibrotic lung diseases and certain cancers, supporting improved patient outcomes and delaying disease progression.