Motixafortide Acetate 1 mg/mL Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 1 mg/mL

Reference Brands: Aphexda (USA)

Category: Oncology Cancer Care

Motixafortide Acetate is a Oncology Cancer Care product available as Injection in strengths 1 mg/mL. It corresponds to the reference brand Aphexda (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Motixafortide, marketed under the brand name Aphexda, is a synthetic cyclic peptide that functions as a selective CXCR4 antagonist and hematopoietic stem cell mobilizer. It is primarily used in patients with multiple myeloma to facilitate the collection of hematopoietic stem and progenitor cells for autologous transplantation. Administered via subcutaneous injection, Motixafortide works by blocking the CXCR4 receptor, disrupting the retention of stem cells in the bone marrow, and promoting their release into the peripheral blood.

The drug is indicated for use in combination with filgrastim, a granulocyte-colony stimulating factor (G-CSF), which enhances stem cell mobilization and improves collection efficiency. This combination provides a predictable and effective method for harvesting sufficient stem cells for transplantation. Motixafortide’s rapid onset and targeted mechanism make it a valuable option in clinical settings, offering a controlled and efficient approach to stem cell mobilization for patients undergoing autologous transplant procedures.