Momelotinib 100 mg, 150 mg, 200 mg Suppliers & Bulk Manufacturers
Available Forms: Tablets
Available Strengths: 100 mg, 150 mg, 200 mg
Reference Brands: Ojjaara (USA)
Category: Oncology Cancer Care
Momelotinib tablets (100–200 mg) are a JAK1/JAK2 inhibitor for myelofibrosis with anaemia, and it can reduce transfusion needs. It is made by GSK as Ojjaara (US) and Omjjara (EU) and is a patented innovator product. Supply is through authorised distribution or named-patient import; ask us which route fits your country.
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Product Description:
Momelotinib is an oral anticancer medication used for the treatment of myelofibrosis, a rare bone marrow disorder characterized by abnormal blood cell production, splenomegaly, and anemia. It is marketed under the brand name Ojjaara and belongs to the class of Janus kinase (JAK) inhibitors. Momelotinib works by inhibiting JAK1 and JAK2 signaling pathways involved in inflammation and abnormal cell proliferation, while also modulating pathways related to anemia, making it a differentiated therapy for patients with myelofibrosis.
Momelotinib is indicated for adult patients with intermediate or high-risk myelofibrosis, including primary myelofibrosis and secondary myelofibrosis arising from polycythemia vera or essential thrombocythemia. The medication is administered orally, offering convenience for long-term disease management.
Common adverse reactions associated with momelotinib therapy include dizziness, fatigue, diarrhea, nausea, thrombocytopenia, hemorrhage, and bacterial infections. Due to these potential effects, patients receiving momelotinib require regular clinical and laboratory monitoring. Overall, momelotinib provides an important targeted treatment option for managing myelofibrosis, particularly in patients with disease-related anemia, supporting improved symptom control and quality of life.
How Momelotinib is supplied today, and licensing ahead of patent expiry
Frequently Asked Questions
Momelotinib is used for the treatment of adult patients with intermediate or high-risk myelofibrosis, including primary myelofibrosis and secondary myelofibrosis following polycythemia vera or essential thrombocythemia. It is particularly beneficial for patients with anemia associated with myelofibrosis.
Momelotinib is a small-molecule kinase inhibitor that targets Janus kinase (JAK) 1 and 2 and activin A receptor type 1 (ACVR1), helping regulate inflammatory signaling and hepcidin production.
The trade name of momelotinib is Ojjaara.
Momelotinib is developed and marketed by GSK (GlaxoSmithKline).
The generic name is momelotinib.
The brand name is Ojjaara.
Momelotinib is manufactured in GMP-compliant pharmaceutical facilities for commercial supply in the United States.
Besides JAK1/JAK2 inhibition, it blocks ACVR1, which lowers hepcidin and improves anaemia, unlike other JAK inhibitors that can worsen it.
200 mg once daily.
No. It is patented and marketed by GSK as Ojjaara (US) and Omjjara (EU).
Momelotinib is sold as Ojjaara and Omjjara. It is developed and sold by GSK. PharmaTradz handles enquiries for authorised supply of the originator product, named-patient import where it is not registered, and licensing or development work ahead of patent expiry.
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