Denileukin Diftitox 300 mcg Suppliers & Bulk Manufacturers
Available Forms: Injection
Available Strengths: 300 mcg
Reference Brands: Lymphir (USA/EU), Ontak (USA/EU)
Category: Oncology Cancer Care
Denileukin diftitox is a recombinant fusion protein combining human interleukin‑2 with fragments of diphtheria toxin. It selectively binds to IL‑2 receptors on malignant T-cells and delivers the toxin to kill these cells. It is used to treat adults with relapsed or refractory Cutaneous T‑cell Lymphoma (CTCL) and requires careful monitoring due to potential serious side effects such as infusion reactions, capillary leak syndrome, and liver toxicity.
Denileukin Diftitox — third party manufacturing & bulk supply
Denileukin Diftitox 300 mcg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
Indicative minimum order quantity
Denileukin Diftitox is supplied as Injection — an injectable dosage form, so the indicative MOQ is 50,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.
Manufacturers of Denileukin Diftitox listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.
Request a quote for Denileukin Diftitox →Frequently Asked Questions
Denileukin diftitox is used to treat adults with persistent or recurrent cutaneous T‑cell lymphoma (CTCL), especially in cases that have relapsed or not responded to at least one prior systemic therapy.
It is a recombinant fusion protein combining human interleukin‑2 (IL‑2) with fragments A and B of diphtheria toxin.
The trade names are Ontak and Lymphir.
The currently marketed version, Lymphir, is manufactured by Citius Pharmaceuticals, Inc.
The generic name is denileukin diftitox.
Brand names are Ontak and Lymphir.
It is produced in an E. coli expression system under Good Manufacturing Practice conditions and supplied by Citius Pharmaceuticals.
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