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Bivalirudin bulk supplier for pharma manufacturers

Bivalirudin Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 250 mg

Reference Brands: Angiomax (USA)

Category: Anaesthetics

Bivalirudin is available in Injection and strengths such as 250 mg. Sourced from GMP-certified and ISO-compliant manufacturers, this API meets global pharmacopeia standards (USP/EP/JP as applicable). Ideal for pharmaceutical formulation and commercial manufacturing, Bivalirudin is supplied in bulk quantities with complete regulatory support including DMF, COA, and MSDS.

Technical Specifications & Supply Details
Lead Time 7 to 60 days (depending on batch size & schedule)
MOQ As per manufacturer’s batch size
COA Available with every batch
Regulatory Dossier / DMF Available upon request
Export Documentation FSC, COA, Manufacturing License, Product Permission
Standards IP, BP, USP
Certifications WHO-GMP, EU-GMP, USFDA (as applicable)

Bivalirudin can be exported to over 30 countries across Asia, Africa, Europe, and Latin America. Flexible packaging, competitive pricing, and a verified supplier network make Pharmatradz a trusted sourcing partner for pharmaceutical companies and contract manufacturers worldwide.

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📘 Sourcing Guide

Product Description:

Bivalirudin is a direct thrombin inhibitor widely used in the management of patients undergoing percutaneous coronary intervention (PCI), particularly in cases of acute myocardial infarction. It plays a critical role in preventing thrombus formation during interventional cardiac procedures by providing rapid, predictable, and controllable anticoagulation. In addition to its established use in PCI, bivalirudin has broader clinical applications, including the management of thromboembolic disorders, cardiopulmonary bypass procedures, and extracorporeal membrane oxygenation, where precise anticoagulant control is essential.

Chemically, bivalirudin is a short, synthetic peptide derived from hirudin, a naturally occurring anticoagulant found in the saliva of the medicinal leech Hirudo medicinalis. It acts by directly and reversibly binding to thrombin, inhibiting both circulating and clot-bound thrombin, as well as thrombin-mediated platelet activation and aggregation. Unlike indirect thrombin inhibitors such as heparin, bivalirudin does not require antithrombin as a cofactor, does not bind to plasma proteins or red blood cells, and does not activate platelets.

Bivalirudin has a rapid onset of action and a short half-life, resulting in a predictable antithrombotic response. Importantly, it carries no risk of heparin-induced thrombocytopenia, making it a reliable alternative to heparin in high-risk patients.

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Frequently Asked Questions


Bivalirudin is used as an anticoagulant to reduce the risk of blood clot formation during percutaneous coronary intervention and other interventional cardiac procedures. It is commonly administered in patients with unstable angina or myocardial infarction undergoing angioplasty and is particularly useful in patients with or at risk of heparin-induced thrombocytopenia.


Bivalirudin is a synthetic peptide composed of 20 amino acids. It is specifically designed to bind directly to thrombin, inhibiting its activity without requiring cofactors such as antithrombin III.


Bivalirudin is marketed under the trade names Angiomax in the United States and Angiox in the European Union and the United Kingdom.


Bivalirudin is manufactured by multiple pharmaceutical companies worldwide, including originator and generic injectable manufacturers that supply hospital and regulated markets, depending on regional approvals.


The generic name of the product is bivalirudin.


The well-known brand names of bivalirudin include Angiomax and Angiox.


Bivalirudin is manufactured in several countries, including the United States, India, and various European countries, by GMP-compliant pharmaceutical manufacturers supplying injectable formulations for hospital use.

Yes, Bivalirudin is available with DMF and other regulatory documents such as COA and MSDS. These can be provided upon request for qualified buyers.

Absolutely. Sample requests are accepted for formulation trials and quality checks. Please submit an enquiry to initiate the process.

Our manufacturing partners are GMP-certified and comply with ISO and WHO standards, ensuring global quality benchmarks.

Lead times vary based on quantity and destination, but most orders are fulfilled within 1–3 weeks. Express shipping options are available.

Yes, Bivalirudin is exported to over 30 countries across Asia, Africa, Europe, and Latin America. We support documentation for customs and regulatory clearance.

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