Belinostat 100 mg/10 mL Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 100 mg/10 mL

Reference Brands: Beleodaq (USA)

Category: Oncology Cancer Care

Belinostat is a Oncology Cancer Care product available as Injection in strengths 100 mg/10 mL. It corresponds to the reference brand Beleodaq (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Belinostat is a novel hydroxamic acid–type histone deacetylase (HDAC) inhibitor with potent antineoplastic activity, marketed under the brand name Beleodaq and previously known as PXD101. It is designed for the treatment of hematological malignancies, including peripheral T-cell lymphoma, as well as certain solid tumors. Belinostat works by targeting HDAC enzymes, which play a key role in regulating gene expression and cellular growth. By inhibiting these enzymes, belinostat promotes tumor cell apoptosis, induces cellular differentiation, inhibits angiogenesis, and suppresses tumor proliferation.

This agent has also shown potential in sensitizing drug-resistant tumor cells to other anticancer therapies, possibly through mechanisms involving the down-regulation of thymidylate synthase, enhancing the efficacy of combination treatments. Belinostat is administered intravenously under medical supervision and is available in precise, standardized dosing to ensure safety and effectiveness in cancer therapy. Developed by TopoTarget and commercialized as Beleodaq, belinostat represents an important option in the targeted treatment of cancers, providing clinicians with a novel mechanism of action to combat malignancies that are difficult to treat with conventional therapies.