Aspirin (Low Dose) Tablet 81 mg Suppliers & Bulk Manufacturers

Available Forms: Tablet

Available Strengths: 81 mg

Reference Brands: -

Category: Blood Disorder

Low-dose aspirin 81 mg tablets, enteric-coated or chewable, for antiplatelet secondary prevention under medical advice. For importers, distributors, pharmacy chains and retail buyers in markets using this strength.

Product Description:

Aspirin 81 mg is the low-dose strength used in North America, about a quarter of the traditional 325 mg tablet. At this dose aspirin acts mainly as an antiplatelet drug, permanently acetylating platelet cyclooxygenase-1 and cutting thromboxane A2 for each platelet's life. Two forms are common. Enteric-coated tablets resist stomach acid and dissolve in the intestine. Chewable tablets act quickly and are the form emergency guidance often advises chewing when a heart attack is suspected.

Daily low-dose aspirin is used for secondary prevention after myocardial infarction, ischaemic stroke or transient ischaemic attack, and in angina or after revascularisation. Guidelines have grown more cautious about starting it for primary prevention, especially in older adults, because of bleeding. Key interactions are anticoagulants, antiplatelets and NSAIDs. Active peptic ulcer, bleeding disorders and aspirin-sensitive asthma rule it out. Enteric-coated tablets are swallowed whole and act too slowly for emergencies.

Sourcing notes. First confirm that 81 mg is a registered strength in your market; where 75 mg or 100 mg is the norm, it may need its own registration. Dossiers are usually abridged, in CTD or ACTD format, and classification as prescription, pharmacy or general-sale medicine varies. For enteric-coated tablets, ask for two-stage dissolution results on the batch CoA, along with free salicylic acid. Aspirin hydrolyses in damp conditions, so Zone IVb stability data matter for tropical markets, with alu-alu blisters or bottles with desiccant. Request the site GMP certificate and a CoPP. Specify coated or chewable, flavour, count per pack and label language.