Pioglitazone And Metformin Tablets bulk supplier for pharma manufacturers

Pioglitazone And Metformin Tablets Suppliers & Bulk Manufacturers

Q: What is generic name of Pioglitazone and Metformin?

The generic name is pioglitazone and metformin.

Q: What is brand name of Pioglitazone and Metformin?

Common brand names include Actoplus Met and Competact.

Available Forms: Tablets

Available Strengths: Pioglitazone 15/30 mg + Metformin 500/850/1000 mg

Reference Brands: Actoplus Met (USA), Competact (EU)

Category: Diabetes

Pioglitazone and metformin fixed-dose tablets for adults with type 2 diabetes, combining an insulin sensitiser with a biguanide, for importers, distributors and hospital buyers checking strength registration.

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Product Description:

This tablet combines pioglitazone, a thiazolidinedione, with metformin, a biguanide. Pioglitazone activates PPAR-gamma receptors and makes fat, muscle and liver more sensitive to insulin. Metformin mainly reduces glucose output by the liver. Both target insulin resistance, the core defect of type 2 diabetes, and neither causes hypoglycaemia without insulin or a sulfonylurea. The page lists pioglitazone 15 mg or 30 mg with metformin 500 mg, 850 mg or 1000 mg; one tablet replaces two, but not every pairing is registered everywhere.

It is used in adults with type 2 diabetes not controlled on metformin alone, or already stable on both separate tablets. Doses are taken with meals, usually twice daily. Pioglitazone causes fluid retention and weight gain, must not be used in significant heart failure, and carries warnings on bladder cancer, fractures in women and macular oedema. Metformin needs adequate kidney function and is paused around iodinated contrast and major surgery because of the rare risk of lactic acidosis. Liver disease and heavy drinking rule it out.

Sourcing notes. Confirm which strength pairs are registered in your market; 15 mg/500 mg and 15 mg/850 mg match the main reference products. Expect a CTD or ACTD dossier with bioequivalence for both components and zone IVb stability where needed. Moisture-protective blisters or bottles are typical, with no cold chain. Ask for a CoA per batch covering assay, dissolution and impurities of both actives, the GMP certificate, a CoPP and a nitrosamine risk assessment, which regulators now expect for metformin products. It is prescription-only. State strength, pack size and labelling language.

Pioglitazone And Metformin Tablets — third party manufacturing & bulk supply

Pioglitazone And Metformin Tablets is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.

Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.

Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Pioglitazone And Metformin Tablets is supplied as Tablets — an oral solid dosage form, so the indicative MOQ is 200,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Pioglitazone And Metformin Tablets listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

Pioglitazone and Metformin is used to improve glycemic control in adults with type 2 diabetes mellitus. Pioglitazone increases insulin sensitivity in peripheral tissues, while Metformin decreases hepatic glucose production and improves insulin action, making the combination effective for lowering blood glucose levels when diet, exercise, or monotherapy are insufficient.

This combination contains pioglitazone hydrochloride, a thiazolidinedione that enhances insulin sensitivity, and metformin hydrochloride, a biguanide that reduces glucose production in the liver and improves insulin-mediated glucose uptake.

The combination is marketed under brand names such as Actoplus Met and Competact in various regions.

It is manufactured by multiple pharmaceutical companies globally, including generic and branded manufacturers approved in different countries.

The generic name is pioglitazone and metformin.

Common brand names include Actoplus Met and Competact.

Pioglitazone and Metformin is manufactured in several countries, including India, the USA, and European nations, by approved pharmaceutical manufacturers.