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Methotrexate Tablet bulk supplier for pharma manufacturers

Methotrexate Tablet 2.5 mg, 10 mg, 25 mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 2.5 mg, 10 mg, 25 mg

Reference Brands: Trexall (US)

Category: Arthritis

Methotrexate tablets inhibit dihydrofolate reductase, disrupting DNA synthesis and cell reproduction. It reduces inflammation and immune activity, making it effective for rheumatoid arthritis, psoriasis, and certain cancers. Benefits include disease modulation, improved joint function, rapid onset, and versatility, with a well-established safety profile when properly monitored.

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Product Description:

Methotrexate tablets are approved in the EU and US for treating rheumatoid arthritis, psoriasis, and certain cancers. In the EU, Pfizer’s Trexall and generic versions are regulated by EMA, supported by dossiers demonstrating safety, efficacy, and manufacturing standards. In the US, FDA approval is based on extensive clinical data and biosimilarity assessments. Both regions require detailed dossiers for initial approval and ongoing pharmacovigilance. For expert assistance with regulatory dossiers, registration, and compliance, visit PharmaTradz. We facilitate efficient market access for methotrexate tablets, ensuring adherence to European and American standards for safe, effective autoimmune and oncological therapy.

Methotrexate Tablet — third party manufacturing & bulk supply

Methotrexate Tablet 2.5 mg, 10 mg, 25 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

What to include when you enquire

  • Destination market — determines which manufacturers hold the right site-level approvals
  • First order quantity and estimated annual volume
  • Whether you need a registration dossier or the product is already registered
  • Packaging, labelling and language requirements
  • Incoterms and required shelf life

Indicative minimum order quantity

Methotrexate Tablet is supplied as Tablets — an oral solid dosage form, so the indicative MOQ is 200,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Methotrexate Tablet listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.

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Frequently Asked Questions

Methotrexate Tablet is used to treat certain types of cancer, severe psoriasis, and rheumatoid arthritis. It works by interfering with the growth of rapidly dividing cells, such as cancer cells, and by suppressing the immune system to reduce inflammation in autoimmune conditions.

Methotrexate Tablet contains the active ingredient methotrexate, a folate antagonist that inhibits the enzyme dihydrofolate reductase. This inhibition prevents DNA synthesis and cell replication, making it effective in slowing or stopping the growth of abnormal cells.

The trade names for Methotrexate include Trexall, Rheumatrex, and Methoblastin, depending on the country and manufacturer.

Methotrexate Tablets are manufactured by several pharmaceutical companies, including Pfizer, Teva Pharmaceuticals, and Sandoz.

The generic name of this product is Methotrexate.

The brand names of Methotrexate include Trexall, Rheumatrex, and Methoblastin.

Methotrexate Tablets are manufactured in multiple countries, including the United States, Germany, and India, by companies such as Pfizer, Teva, and Sandoz, depending on regional market supply.

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